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Search Results for " Stem Cells "

ターゲット

Casein Kinase

147

阻害剤

天然化合物

259

リコンビナントタンパク質

ライブラリー

カタログ番号	製品名	別名	ターゲット
T8987	Epiblastin A		Casein Kinase
	Epiblastin A is an inhibitor of Casein Kinase 1 (CK1). Epiblastin A engages CK1 isoenzymes in cell lysate and induces efficient conversion of epiblast stem cells (EpiSCs) into embryonic stem cells (cESCs).		Casein Kinase
T16695	Pyrintegrin		Integrin
	Pyrintegrin is an β1-integrin agonist that promotes embryonic stem cells' survival. Pyrintegrin can be used as a podocyte-protective agent. Pyrintegrin enhances cell-extracellular matrix adhesion-mediated integrin signal...		Integrin
T1748	Kartogenin	KGN	TGF-beta/Smad
	Kartogenin (KGN) is an activator of the smad4/smad5 pathway, and promotes the selective differentiation of multipotent mesenchymal stem cells into chondrocytes.		TGF-beta/Smad
T2040	OAC1	BAS 00287861	OCT
	OAC1 (BAS 00287861) is a compound activating Octamer-binding transcription factor 4 (Oct4). It enhances the iPSC reprogramming efficiency and accelerates the reprogramming process.		OCT
T2161	Cardiogenol C		Wnt/beta-catenin
	Cardiogenol C is a cardiomyogenesis inducer in embryonic stem cells.		Wnt/beta-catenin
T0432	Diclofenac diethylamine		Apoptosis , COX
	Diclofenac Diethylamine, a non-selective COX inhibitor, is utilized as a nonsteroidal anti-inflammatory drug (NSAID).		Apoptosis , COX
T2052	KY02111		Wnt/beta-catenin
	KY02111 facilitates differentiation of hPSCs to cardiomyocytes by inhibiting Wnt signaling, maybe affect downstream of GSK3β and APC.		Wnt/beta-catenin
T10904	CWP232228		Wnt/beta-catenin
	CWP232228, a potent and selective Wnt / β-catenin signaling inhibitor, antagonizes the binding of β-catenin to T-cell factor (TCF) in the nucleus. CWP232228 inhibits the formation and metastasis of tumors by inhibiting t...		Wnt/beta-catenin
T21981	Phthalazinone pyrazole		Aurora Kinase
	Phthalazinone pyrazole is potent, selective, and orally bioavailable inhibitor of Aurora-A kinase. Aurora-A is overexpressed in a variety of tumor types and displays oncogenic activity.		Aurora Kinase
T0196	Diclofenac	Diclofenacum,Voltaren	Apoptosis , COX
	Diclofenac (Diclofenacum) is a nonsteroidal benzeneacetic acid derivative with anti-inflammatory activity. Diclofenac binds and chelates both isoforms of cyclooxygenase (COX-1 and-2), thereby blocking the conversion of a...		Apoptosis , COX
T6470	Diclofenac Potassium	CGP-45840B,Cataflam,Voltfast	Apoptosis , Others , COX
	Diclofenac Potassium (CGP-45840B) is a nonsteroidal anti-inflammatory drug taken to reduce inflammation and as an analgesic reducing pain in certain conditions.		Apoptosis , Others , COX
T1555	Diclofenac sodium	GP 45840	Apoptosis , COX
	Diclofenac sodium (GP 45840) is a non-steroidal anti-inflammatory agent (NSAID) with antipyretic and analgesic actions. It is primarily available as the sodium salt.		Apoptosis , COX
T0640	Benzyl butyl phthalate	BBP,1,2-benzenedicarboxylic acid,butyl phenylmethyl ester,Butyl benzyl phthalate	Others , Aryl Hydrocarbon Receptor
	Benzyl butyl phthalate (1,2-benzenedicarboxylic acid) is used as a plasticizer for PVC.		Others , Aryl Hydrocarbon Receptor
T8005	Cardiogenol C hydrochloride	Cardiogenol C HCl,Cardiogenol C	Wnt/beta-catenin
	Cardiogenol C hydrochloride (Cardiogenol C) can induces the differentiation of ESCs into cardiomyocytes (EC50= 100 nM).		Wnt/beta-catenin
T3221	Oct3/4-inducer-1	2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile	Others , OCT
	Oct3/4-inducer-1 (2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile) is an OCT3/4 inducer that promotes the expression and stabilization of OCT3/4 and enhances its transcriptional activity in a variety of human cells.		Others , OCT
T1776	Plerixafor	JM3100,AMD 3100,AMD-3329	Virus Protease , HIV Protease , CXCR
	Plerixafor (AMD-3329), a chemokine receptor antagonist, blocks the binding of stromal cell-derived factor (SDF-1alpha) to the cellular receptor CXCR4.		Virus Protease , HIV Protease , CXCR
T1725	Y-27632 dihydrochloride	Y-27632 2HCl	ROCK , Apoptosis
	Y-27632 dihydrochloride (Y-27632 2HCl) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 dihydrochloride also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells.		ROCK , Apoptosis
T4399	ML239	CID-49843203	Others
	ML239 (CID-49843203) is a potent and selective inhibitor of breast cancer stem cells, with an IC50 of 1.16 μM.		Others
T3684	CP21R7	CP21	GSK-3 , PKC
	CP21R7 (CP21) is an effective and specific GSK3β inhibitor. It is used as an activator of stem cells prior to the induction of differentiation of stem cells to smooth muscle and endothelial cells. CP21R7 can be combined ...		GSK-3 , PKC
T8400	Pamidronic acid		Wnt/beta-catenin
	Pamidronic acid Leads to Bone Necrosis via Suppression of Wnt/β-Catenin Signaling in Human Bone Marrow Mesenchymal Stem Cells		Wnt/beta-catenin
T24580	P18IN003	P18IN 003,P18IN-003	CDK
	P18IN003 is a selective and effective p18(INK4C) inhibitor that inhibits the activity of p18 protein and can be used to study in vitro expansion of hematopoietic stem cells.		CDK
TP1024	Rusalatide acetate (497221-38-2 free base)	Rusalatide acetate,TP508 amide acetate	Others
	Rusalatide acetate (TP508 amide acetate), a regenerated peptide, alleviates radiation-induced gastrointestinal injury by activating stem cells and protecting recess integrity.		Others
T16754	RIPGBM		Apoptosis
	RIPGBM is a selective inducer of apoptosis in glioblastoma multiforme cancer stem cells (EC50: ≤500 nM).		Apoptosis
T40222	FTO-IN-3		Others
	FTO-IN-3 is a FTO inhibitor. FTO-IN-3 impairs self-renewal in glioblastoma stem cells.		Others
T3589	NSC23005 Sodium		CDK
	NSC23005 sodium is a novel and effective p18 inhibitor (ED50=5.21 nM) in promoting Hematopoietic stem cells (HSCs) expansion in both murine and human models.		CDK
T23446	TCS 2210		Others
	TCS 2210 is an inducer of neuronal differentiation in mesenchymal stem cells and increases the neuronal markers β-III tubulin expression and neuron-specific enolase expression.		Others
T28866	Stemazole		Apoptosis
	Stemazole is a novel small molecule human stem/progenitor cell proliferation activator that promotes the survival of human embryonic stem cells and maintains stemness, and promotes the survival of oligodendrocyte precurs...		Apoptosis
T11469	GSK-3484862		DNA Methyltransferase
	GSK-3484862 is a non-covalent Dnmt1 inhibitor. It induces DNA hypomethylation to against cancer.		DNA Methyltransferase
T8786	VUT-MK142		Others
	VUT-MK142 is a new cardiomyogenic small molecule promoting the differentiation of pre-cardiac mesoderm into cardiomyocytes,which may be useful to differentiate stem cells into cardiomyocytes for cardiac repair.		Others
T16680	PTC-028		Apoptosis , BMI-1
	PTC-028 selectively suppresses cancer cells whereas normal cells remain unaffected. PTC-028 is an orally bioavailable inhibitor of stem cell factor BMI-1 in ovarian cancer. The depletion of BMI-1 by PTC-028 causes caspas...		Apoptosis , BMI-1
T1870	Y-27632		ROCK , Apoptosis
	Y-27632 dihydrochloride (Y-27632 2HCl) is an orally potent, ATP-competitive inhibitor of ROCK-I and ROCK-II. Y-27632 dihydrochloride also inhibits isolation-induced apoptosis in mouse prostate stem or progenitor cells.		ROCK , Apoptosis
TP1828	N-Acetyl-Ser-Asp-Lys-Pro		RAAS
	Acetyl Ser-Asp-Lys-Pro is formed in bone marrow cells by enzymatic processing of thymosin β4. It inhibits the entry of pluripotent hemopoietic stem cells into S-phase of the cell cycle and protects against Ara-C lethalit...		RAAS
T3162	IDE1		Others
	IDE1 can induce definitive endoderm from embryonic stem cells. It has been shown to induce the differentiation of Sox17+/FoxA2+-expressing pancreatic progenitors from human and mouse embryonic stems cells (EC50: 125.5 nM...		Others
T11053	DJ001		Phosphatase
	DJ001 is a highly specific, selective and non-competitive protein tyrosine phosphatase σ (PTPσ) inhibitor with IC50 of 1.43 μM. DJ001 promotes the regeneration of hematopoietic stem cells.		Phosphatase
T2019	OAC2		OCT
	OAC2 is an Oct4 activator which activates expression through the Oct4 gene promoter; enhances reprogramming efficiency by increasing the rate of production of induced pluripotent stem cells (iPSCs) from embryonic fibrobl...		OCT
T9996	NCT-58	NCT58	HSP
	NCT-58 is a potent C-terminal HSP90 inhibitor. NCT-58 does not induce the heat shock response (HSR). NCT-58 elicits anti-tumor activity via the simultaneous downregulation of HER family members as well as inhibition of ...		HSP
T60143	MitoBloCK-6		Apoptosis
	MitoBloCK-6 is a potent Erv1/ALR inhibitor, with an IC 50 of 900 nM and 700 nM, respectively. MitoBloCK-6 also inhibits Erv2 with IC 50 of 1.4 μM. MitoBloCK-6 can induce apoptosis via cytochrome c release in human embryo...		Apoptosis
T1726	SB-431542	SB 431542	ALK , TGF-beta/Smad
	SB-431542 is an inhibitor of ALK5/TGF-β type I Receptor (IC50=94 nM) and is selective. SB 431542 also has inhibitory activity against ALK4 and ALK7 but not other proteins. SB 431542 can be used for induced differentiatio...		ALK , TGF-beta/Smad
T2310	CHIR-99021	Laduviglusib,CT99021,CHIR-99021	GSK-3 , Wnt/beta-catenin , Autophagy
	CHIR-99021 (CT99021) is an activator of the Wnt/β-catenin signaling pathway and a GSK-3α/β inhibitor (IC50=10/6.7 nM) with selective and oral activity.CHIR-99021 induces cellular autophagy, which enhances self-renewal in...		GSK-3 , Wnt/beta-catenin , Autophagy
T24754	Hh-Ag1.5	SAG-1.5,SAG1.5,SAG 1.5	Hedgehog/Smoothened
	Hh-Ag1.5 (SAG-1.5) is a potent Hedgehog (Hh) agonist (EC50: 1 nM) and Smoothened (Smo) receptor agonist, with an EC50 of 1 nM and Ki values between 0.5 and 2.3 nM for Smo. Hh-Ag1.5-mediated reprogramming breaks the quies...		Hedgehog/Smoothened
T14973	CITCO		Apoptosis , Others
	CITCO inhibits growth and expansion of brain tumour stem cells (BTSCs) and has an EC50 of 49 nM over pregnane X receptor (PXR), and no activity on other nuclear receptors. CITCO is an imidazothiazole derivative and it al...		Apoptosis , Others
T2301	SB 202190	FHPI,SB202190	Apoptosis , p38 MAPK , Autophagy
	SB 202190 (FHPI) is a p38 MAPK inhibitor that inhibits p38α and p38β2 (IC50=50/100 nM) selectively and cell-permeably. SB 202190 has antitumor activity and also induces the differentiation of human embryonic stem cells i...		Apoptosis , p38 MAPK , Autophagy
TP2496	Octapeptide-2 Acetate	Octapeptide-2 Acetate(1374396-34-5 Free base)	Others
	Octapeptide-2 Acetate, as a hair growth promotion active, is a double-layered encapsulated biomimetic peptide that helps increase cell growth and migration. It promotes hair growth by activating the stem cells of the hai...		Others
T22814	GSA-10		Hedgehog/Smoothened
	Smoothened (Smo) receptor agonist		Hedgehog/Smoothened
T77701	FL118	FL 118,FL-118,10,11-(Methylenedioxy)-20(S)-camptothecin	Survivin
	FL118 is a novel survivin inhibitor that inhibits cancer stem cell-like properties.FL118 is a novel camptothecin analog with anticancer activity that inhibits epithelial-mesenchymal transition through the Wnt/β-catenin s...		Survivin
T3637	Pifithrin-β hydrobromide	Cyclic PFT-α,PFT-β,Cyclic Pifithrin-α hydrobromide,Pifithrin-β,PFT β (hydrobromide)	Ferroptosis , p53
	Pifithrin-β hydrobromide (Cyclic PFT-α) is an inhibitor of p53; reversibly blocks p53-dependent transcriptional activation and apoptosis. Protects against neuronal death in models of stroke and neurodegenerative disorder...		Ferroptosis , p53
T3317	SZL P1-41		Apoptosis , Others , E1/E2/E3 Enzyme
	SZL P1-41, a skp2 inhibitor, can prevent assembly of Skp2-Skp1 complexes. It selectively suppresses Skp2 SCF E3 ligase activity but exhibits no effect on the activity of other SCF complexes. It also inhibits Skp2-mediate...		Apoptosis , Others , E1/E2/E3 Enzyme
T4126	CBL0137	Curaxin 137,CBLC137	NF-κB , p53
	CBL0137 (Curaxin 137), a metabolically stable curaxin, activates p53 (EC50: 0.37 μM) and inhibits NF-κB (EC50: 0.47 μM). It functionally inactivates the facilitates chromatin transcription complex (FACT), driving the eff...		NF-κB , p53
T2310L	CHIR-99021 HCl	CT99021 HCl,Laduviglusib HCl	GSK-3
	CHIR-99021 HCl (Laduviglusib HCl) is a highly potent and selective inhibitor of GSK-3α/β, with IC50 values of 10 nM and 6.7 nM respectively. It demonstrates remarkable selectivity for GSK-3, with over 500-fold selectivit...		GSK-3
T21493	Cyclosporin H		Others
	Cyclosporin H (CsH), a specific inhibitor of FPR1, inhibited lung inflammation in the ALI models. CsH significantly attenuated MTDs or NFP-induced inflammatory lung injury and activation of MAPK and AKT pathways. Cyclosp...		Others

Compounds

Epiblastin A

T8987

Synonym:

Target: Casein Kinase

Target: TGF-beta/Smad

OAC1

T2040

Synonym: BAS 00287861

Target: Wnt/beta-catenin

Diclofenac diethylamine

T0432

Synonym:

Target: Apoptosis, COX

KY02111

T2052

Synonym:

Target: Wnt/beta-catenin

CWP232228

T10904

Synonym:

Target: Wnt/beta-catenin

Phthalazinone pyrazole

T21981

Synonym:

Target: Aurora Kinase

Diclofenac

T0196

Synonym: Diclofenacum,Voltaren

Target: Apoptosis, COX

Diclofenac Potassium

T6470

Synonym: CGP-45840B,Cataflam,Voltfast

Target: Apoptosis, Others, COX

Diclofenac sodium

T1555

Synonym: GP 45840

Target: Apoptosis, COX

Benzyl butyl phthalate

T0640

Synonym: BBP,1,2-benzenedicarboxylic acid,butyl phenylmethyl ester,Butyl benzyl phthalate

Target: Others, Aryl Hydrocarbon Receptor

Cardiogenol C hydrochloride

T8005

Synonym: Cardiogenol C HCl,Cardiogenol C

Target: Wnt/beta-catenin

Oct3/4-inducer-1

T3221

Synonym: 2-(4-(4-methoxybenzyloxy)phenyl)acetonitrile

Target: Others, OCT

Plerixafor

T1776

Synonym: JM3100,AMD 3100,AMD-3329

Target: Virus Protease, HIV Protease, CXCR

Y-27632 dihydrochloride

T1725

Synonym: Y-27632 2HCl

Target: ROCK, Apoptosis

ML239

T4399

Synonym: CID-49843203

Target: Wnt/beta-catenin

P18IN003

T24580

Synonym: P18IN 003,P18IN-003

Target: CDK

Rusalatide acetate (497221-38-2 free base)

TP1024

Synonym: Rusalatide acetate,TP508 amide acetate

Target: DNA Methyltransferase

Target: Apoptosis, BMI-1

Y-27632

T1870

Synonym:

Target: ROCK, Apoptosis

N-Acetyl-Ser-Asp-Lys-Pro

Target: ALK, TGF-beta/Smad

CHIR-99021

T2310

Synonym: Laduviglusib,CT99021,CHIR-99021

Target: GSK-3, Wnt/beta-catenin, Autophagy

Hh-Ag1.5

T24754

Synonym: SAG-1.5,SAG1.5,SAG 1.5

Target: Hedgehog/Smoothened

CITCO

T14973

Synonym:

Target: Apoptosis, Others

SB 202190

T2301

Synonym: FHPI,SB202190

Target: Apoptosis, p38 MAPK, Autophagy

Octapeptide-2 Acetate

TP2496

Synonym: Octapeptide-2 Acetate(1374396-34-5 Free base)

Target: Hedgehog/Smoothened

FL118

T77701

Synonym: FL 118,FL-118,10,11-(Methylenedioxy)-20(S)-camptothecin

Target: Survivin

Pifithrin-β hydrobromide

T3637

Synonym: Cyclic PFT-α,PFT-β,Cyclic Pifithrin-α hydrobromide,Pifithrin-β,PFT β (hydrobromide)

Target: Ferroptosis, p53

SZL P1-41

T3317

Synonym:

Target: Apoptosis, Others, E1/E2/E3 Enzyme

CBL0137

T4126

Synonym: Curaxin 137,CBLC137

Target: NF-κB, p53

CHIR-99021 HCl

T2310L

Synonym: CT99021 HCl,Laduviglusib HCl

カタログ番号	製品名	別名	ターゲット
TN2883	3',4'-Dimethoxyflavone		Others , PARP
	3',4'-Dimethoxyflavone is a standard compound of flavonoids with numerous medicinal activities.		Others , PARP
T1048	Estradiol	E2,17β-Estradiol,17β-Oestradiol,β-Estradiol	Estrogen Receptor/ERR , Estrogen/progestogen Receptor , Endogenous Metabolite
	Estradiol (E2) is a naturally occurring steroidal sex hormone that is essential for female fertility and maintenance of secondary sexual characteristics. Estradiol upregulates IL-6 expression through estrogen receptor be...
TN7036	N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide	(9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide,Macamide Impurity 14	Wnt/beta-catenin
	N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide (Macamide Impurity 14) induces osteogenic differentiation and subsequent bone formation of mesenchymal stem cells by activating the canonical Wnt/β-catenin signaling pa...		Wnt/beta-catenin
TMO2681	Xanthosine	9-Beta-D-Ribofuranosylxanthine,Xanthine riboside	Others , Endogenous Metabolite
	Xanthosine (9-Beta-D-Ribofuranosylxanthine) is a xanthine nucleoside that increases the number of mammary stem cells and milk production in goats and cattle.		Others , Endogenous Metabolite
TN2081	Maohuoside A		MAPK
	Maohuoside A promotes osteogenesis of rat mesenchymal stem cells via BMP and MAPK signaling pathways.		MAPK
T0906	Salinomycin	Procoxacin	Wnt/beta-catenin , Antibacterial
	Salinomycin (Procoxacin), a polyether potassium ionophore antibiotic, specifically inhibits the growth of gram-positive bacteria. It acts as a potent inhibitor of Wnt/β-catenin signaling, blocking Wnt-induced LRP6 phosph...		Wnt/beta-catenin , Antibacterial
T3916	Ginsenoside F2		Apoptosis , Endogenous Metabolite , Autophagy
	Ginsenoside F2 has antiproliferative activity against breast cancer stem cells (CSCs). It induces apoptosis in breast CSCs by activating the intrinsic apoptotic pathway and mitochondrial dysfunction.		Apoptosis , Endogenous Metabolite , Autophagy
T1257	Bestatin	Ubenimex	Others , Aminopeptidase , Antibacterial , Antibiotic , LTR
	Bestatin (Ubenimex) competitively inhibits many aminopeptidases, including B, N and leucine aminopeptidases. Ubenimex is a microbial metabolite and dipeptide with potential immunomodulatory and antitumor activities. Amin...		Others , Aminopeptidase , Antibacterial , Antibiotic , LTR
T4S1050	Pristimerin	Celastrol methyl ester	NF-κB , Antibacterial
	1. Pristimerin (Celastrol methyl ester) has anticancer activity , treatment with Pristimerin may be a potential strategy for the suppression of hypoxia-induced metastasis through the reversal of hypoxia-induced stem cell...		NF-κB , Antibacterial
T3S2312	Poncirin	Isosakuranetin-7-neohesperidoside	Apoptosis , Others
	1. Poncirin (Isosakuranetin-7-neohesperidoside) shows a significant in vitro inhibitory effect on the growth of the human gastric cancer cells, SGC-791, in a dose-dependent manner. 2. Poncirin prevents adipogenesis, enha...		Apoptosis , Others
TL0008	Gigantol		Wnt/beta-catenin , Glucosidase
	Gigantol is a novel inhibitor of the Wnt/β-catenin pathway. It inhibits Wnt/β-catenin signaling through downregulation of phosphorylated LRP6 and cytosolic β-catenin in breast cancer cells. Gigantol may be developed as a...		Wnt/beta-catenin , Glucosidase
T4915	β-Glycerophosphate disodium salt hydrate		Phosphatase , Endogenous Metabolite
	β-Glycerophosphate is a classical serine-threonine phosphatase inhibitor used in kinase reaction buffers. BGP is often used in combination with other phosphatase/protease inhibitors for broad spectrum inhibition. It func...		Phosphatase , Endogenous Metabolite
T5S0896	Loureirin A		Akt , PI3K
	Loureirin A has an inhibitory effect on platelet activation, perhaps through an impairment of PI3K/Akt signaling.Loureirin A negatively affects agonist-induced platelet aggregation such as collagen, collagen-related pept...		Akt , PI3K
T3S0027	Picropodophyllotoxin	AXL 1717,Picropodophyllin	IGF-1R
	Picropodophyllotoxin (AXL 1717) is a cyclolignan alkaloid found in the mayapple plant family (Podophyllum peltatum), and a small molecule inhibitor of the insulin-like growth factor 1 receptor (IGF1R) with potential anti...		IGF-1R
TN4082	Friedelin 3,4-lactone		Others
	Friedelin-3,4-lactone has a promotion effect on the inducing proliferation of rat mesenchymal stem cells(rMSCs).		Others
TN6568	Glycinol
	Glycinol enhances osteogenic differentiation and attenuates the effects of age on mesenchymal stem cells, it could as a potential preventive or treatment for osteoporosis. Glycinol also has antidiuretic activity.
TN3215	7,4'-Dihydroxy-8-methylflavan		Others
	7,4'-Dihydroxy-8-methylflavan can significantly promote mesenchymal stem cells (MSCs) osteogenic differentiation by increasing the levels of alkaline phosphatase (ALP) activity. 7,4'-Dihydroxy-8-methylflavan also has fre...		Others
T82310	Glomeratide A
	Glomeratide A, a benzophenone C-glucoside, exhibits hepatoprotective properties and safeguards rat liver epithelial stem-like cells from d-galactosamine-induced hepatotoxicity.
T71471	Chrysotobibenzyl
	Chrysotobibenzyl, a bibenzyl found in the stem of Dendrobium pulchellum, may facilitate anoikis--a form of programmed cell death that occurs in anchorage-dependent cells when they detach from the surrounding extracellula...
T75661	Thymopentin acetate
	Thymopentin acetate, primarily secreted by the epithelial cells of the thymic cortex and medulla, serves as an effective immunomodulatory agent. It possesses a short plasma half-life of 30 seconds and significantly enhan...

天然物製品

3',4'-Dimethoxyflavone

Synonym: E2,17β-Estradiol,17β-Oestradiol,β-Estradiol

Target: Estrogen Receptor/ERR, Estrogen/progestogen Receptor, Endogenous Metabolite

N-(3-Methoxybenzyl)-(9Z,12Z,15Z)-octadecatrienamide

TN7036

Synonym: (9Z,12Z,15Z)-N-[(3-Methoxyphenyl)methyl]-9,12,15-octadecatrienamide,Macamide Impurity 14

Target: Wnt/beta-catenin

Xanthosine

TMO2681

Synonym: 9-Beta-D-Ribofuranosylxanthine,Xanthine riboside

Target: Others, Endogenous Metabolite

Target: Wnt/beta-catenin, Antibacterial

Ginsenoside F2

T3916

Synonym:

Target: Apoptosis, Endogenous Metabolite, Autophagy

Bestatin

T1257

Synonym: Ubenimex

Target: Others, Aminopeptidase, Antibacterial, Antibiotic, LTR

Pristimerin

T4S1050

Synonym: Celastrol methyl ester

Target: NF-κB, Antibacterial

Poncirin

T3S2312

Synonym: Isosakuranetin-7-neohesperidoside

Target: Apoptosis, Others

Gigantol

TL0008

Synonym:

Target: Wnt/beta-catenin, Glucosidase

β-Glycerophosphate disodium salt hydrate

T4915

Synonym:

Target: Phosphatase, Endogenous Metabolite

Synonym: AXL 1717,Picropodophyllin

Target: IGF-1R

Friedelin 3,4-lactone

7,4'-Dihydroxy-8-methylflavan

Recombinant Proteins

Species：

Expression System：

Tag：

カタログ番号	製品名	Species	Expression System
TMPJ-01065	Noggin/NOG Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Noggin is a secreted homodimeric glycoprotein that is an antagonist of bone morphogenetic proteins (BMPs). Mouse Noggin cDNA encodes a 232 amino acid (aa) residue precursor protein with 19 aa residue putative signal pept...
TMPY-05004	FGF-4 Protein, Human, Recombinant	Human	E. coli
	FGF (fibroblast growth factor) signalling is known to be required for many aspects of mesoderm formation and patterning during Xenopus development and has been implicated in regulating genes required for the specificati...
TMPY-01410	IL-3R alpha/CD123 Protein, Human, Recombinant (His)	Human	HEK293
	Interleukin-3 receptor subunit alpha, also known as IL-3 receptor subunit alpha, IL-3R-alpha, CD123, and IL3RA, is a single-pass type I membrane protein that belongs to the type I cytokine receptor family and Type 5 subf...
TMPY-03066	FLT3 Ligand Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of th...
TMPY-05636	G-CSF Protein, Mouse, Recombinant	Mouse	HEK293
	Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial...
TMPY-04829	G-CSF Protein, Human, Recombinant	Human	HEK293
	Granulocyte-colony stimulating factor (G-CSF) is a growth factor and an essential cytokine belonging to the CSF family of hormone-like glycoproteins. It is produced by numerous cell types including immune and endothelial...
TMPY-03215	FLT3 Ligand Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of th...
TMPY-06873	FLT3 Ligand Protein, Human, Recombinant	Human	E. coli
	FLT3L, also known as flt3 ligand, is a small molecule that acts as a growth factor that increases the number of immune cells by activating the hematopoietic progenitors. In vivo, FLT3L also induces the mobilization of th...
TMPY-03835	CDCP1 Protein, Rhesus, Recombinant (His)	Rhesus	HEK293
	CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, ...
TMPY-06842	BMP-4 Protein, Human, Recombinant (E399D)	Human	E. coli
	BMP4 (bone morphogenetic protein-4)-directed differentiation of human embryonic stem cells (ESCd). Autophagy is a conserved catabolic process with complicated roles in tumor development. Bone morphogenetic protein 4 (BMP...
TMPY-04298	CDCP1 Protein, Human, Recombinant (His)	Human	HEK293
	CDCP1 contains three extracellular CUB domains. It is a putative stem cell marker that is highly expressed in some human cancer cells and both, typical and atypical (cancerous) colons. It interacts with CDH2/N-cadherin, ...
TMPY-03947	CD48 Protein, Human, Recombinant (hFc)	Human	HEK293
	Cluster of Differentiation 48 (CD48), also known as SLAMF2, BCM-1 and BLAST-1, is a GPI-linked protein belonging to the CD2 subfamily of immunoglobulin superfamily molecules. CD2 and 2B4 (CD244) are known ligands for CD4...
TMPY-00130	VISTA Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	VSIR (V-Set Immunoregulatory Receptor, also known as VISTA) is a Protein Coding gene. VISTA is an immunoregulatory receptor that inhibits the T-cell response. It may promote differentiation of embryonic stem cells, by in...
TMPY-02268	CD93/C1qR1 Protein, Human, Recombinant (His)	Human	HEK293
	CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protei...
TMPY-06844	CD93/C1qR1 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protei...
TMPY-06027	CD93/C1qR1 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	CD93 or C1q receptor 1 (C1qR) is an about 120 kDa O-sialoglycoprotein that within the hematopoietic system is selectively expressed on cells of the myeloid lineage. CD93/C1qR is a highly glycosylated transmembrane protei...
TMPY-03219	VISTA Protein, Human, Recombinant (His)	Human	HEK293
	VSIR (V-Set Immunoregulatory Receptor, also known as VISTA) is a Protein Coding gene. VISTA is an immunoregulatory receptor that inhibits the T-cell response. It may promote differentiation of embryonic stem cells, by in...
TMPY-03532	LIF Protein, Human, Recombinant (His)	Human	HEK293
	Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met...
TMPY-04104	LIF Protein, Human, Recombinant	Human	HEK293
	Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met...
TMPY-04278	LIF Protein, Mouse, Recombinant	Mouse	HEK293
	Leukemia inhibitory factor (LIF) is a pleiotropic glycoprotein belonging to the IL-6 family of cytokines. It is involved in growth promotion and cell differentiation of different types of target cells, influence bone met...
TMPY-01384	Endoglin/CD105 Protein, Human, Recombinant (His)	Human	HEK293
	Endoglin, also known as CD105, is a type I homodimeric transmembrane glycoprotein with a large, disulfide-linked, extracellular region and a short, constitutively phosphorylated cytoplasmic tail. Endoglin contains an RGD...
TMPJ-00051	IL-3 Protein, Mouse, Recombinant (His)	Mouse	Human Cells
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPY-01148	TREM-2 Protein, Human, Recombinant (His)	Human	HEK293
	Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b...
TMPY-00432	TREM-2 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b...
TMPY-01703	TREM-2 Protein, Mouse, Recombinant (His)	Mouse	HEK293
	Triggering receptor expressed on myeloid cells 2 ( TREM2 ) is a single Ig domain receptor. It is expressed on macrophages and dendritic cells but not on granulocytes or monocytes. Its expression is most abundant in the b...
TMPY-01578	CD166/ALCAM Protein, Human, Recombinant (His)	Human	HEK293
	Activated leukocyte cell adhesion molecule (ALCAM)/Cluster of differentiation (CD166) is a type I transmembrane cell adhesion molecule belonging to the Ig superfamily and a ligand for CD6 that is expressed on T lymphocyt...
TMPY-05446	CD200 Protein, Human, Recombinant (hFc)	Human	HEK293
	CD200 (OX-2) is a cell surface glycoprotein that imparts immune privileges by suppressing alloimmune and autoimmune responses through its receptor, CD200R, expressed primarily on myeloid cells. Signals delivered through ...
TMPY-00464	M-CSF/CSF1 Protein, Mouse, Recombinant	Mouse	HEK293
	Macrophage colony-stimulating factor 1, also known as CSF-1, M-CSF, Lanimostim and CSF1, is a single-pass membrane protein which is disulfide-linked as a homodimer or heterodimer. Granulocyte / macrophage colony-stim...
TMPY-02170	SCF Protein, Human, Recombinant (aa 1-189, His)	Human	Baculovirus-Insect Cells
	Similar to Kit ligand precursor (C-kit ligand), also known as Stem cell factor (SCF), Mast cell growth factor (MGF), or Hematopoietic growth factor KL. SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encod...
TMPY-01247	FLT3 Protein, Human, Recombinant (T227M, His)	Human	HEK293
	The cluster of differentiation (CD) system is commonly used as cell markers in Immunophenotyping. Different kinds of cells in the immune system can be identified through the surface CD molecules which associating with th...
TMPY-02105	SCF Protein, Mouse, Recombinant (His)	Mouse	Baculovirus-Insect Cells
	Similar to Kit ligand precursor (C-kit ligand), also known as Stem cell factor (SCF), Mast cell growth factor (MGF), or Hematopoietic growth factor KL. SCF/C-kit ligand is the ligand of the tyrosine-kinase receptor encod...
TMPY-00021	PADI4 Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	Protein-arginine deiminase type-4, also known as HL-6 PAD, Peptidylarginine deiminase IV, Protein-arginine deiminase type I V and PADI4, is a cytoplasm and nucleus protein that belongs to the protein arginine deiminase f...
TMPY-04356	GSK3B Protein, Human, Recombinant (His)	Human	Baculovirus-Insect Cells
	GSK3B is a serine-threonine kinase, belonging to the glycogen synthase kinase subfamily. It Contains 1 protein kinase domain, and is expressed in the testis, thymus, prostate, and ovary and weakly expressed in the lung, ...
TMPY-01084	TrkA Protein, Human, Recombinant (His)	Human	HEK293
	TRKA is a member of the neurotrophic tyrosine kinase receptor (NTKR) family. It is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. Isoform TrkA-III promot...
TMPK-00590	IL-3 Protein, Human, Recombinant（E. coli）	Human	E. coli
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00655	IL-3 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	E. coli
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00031	IL-3 Protein, Human, Recombinant (His & Avi)	Human	E. coli
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00033	IL-3 Protein, Human, Recombinant (hFc)	Human	HEK293
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-00032	IL-3 Protein, Human, Recombinant (His & Avi), Biotinylated	Human	E. coli
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPJ-00879	HOXB4 Protein, Human,Recombinant (L175D, E176K, E178K, His)	Human	E. coli
	Homeobox B4 (HOXB4) is encoded by the HOXB4 gene which is a member of the the class I homeobox (HOX) gene family and encodes a nuclear protein with a homeobox DNA-binding domain. These genes are master control regulators...
TMPK-00049	IL-3 Protein, Mouse, Recombinant (hFc)	Mouse	HEK293
	Interleukin 3 is a pleiotropic factor produced primarily by activated T cells that can stimulate the proliferation and differentiation of pluripotent hematopoietic stem cells as well as various lineage committed progenit...
TMPK-01002	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (hFc & Avi), Biotinylated	Human	HEK293
	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic b...
TMPK-01004	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (aa 65-265, hFc)	Human	HEK293
	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic b...
TMPK-00548	CLEC12A/MICL/CLL-1 Protein, Cynomolgus, Recombinant (His)	Cynomolgus	HEK293
	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic b...
TMPK-01003	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His, Avi), Biotinylated	Human	HEK293
	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic b...
TMPK-01006	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (aa 65-265, His)	Human	HEK293
	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic b...
TMPK-00995	CLEC12A/MICL/CLL-1 Protein, Mouse, Recombinant (aa 65-267, His)	Mouse	HEK293
	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic b...
TMPK-01005	CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His), FITC-Labeled	Human	HEK293
	CLEC12A has recently been identified as an antigen, expressed on leukemic stem cells and leukemic blasts. Given the fact that this expression profile seems stable throughout diagnosis, treatment and relapse on leukemic b...
TMPH-02579	CHRDL1 Protein, Mouse, Recombinant (His & Myc)	Mouse	Baculovirus
	Seems to antagonize the function of BMP4 by binding to it and preventing its interaction with receptors. Alters the fate commitment of neural stem cells from gliogenesis to neurogenesis. Contributes to neuronal different...
TMPH-02316	YJEFN3 Protein, Human, Recombinant	Human	E. coli
	May accelerate cholesterol efflux from endothelial cells to high-density lipoprotein (HDL) and thereby regulates angiogenesis. May orchestrate hematopoietic stem and progenitor cell emergence from the hemogenic endotheli...
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Noggin/NOG Protein, Mouse, Recombinant (His)

TMPJ-01065

Species: Mouse

Expression System: Human Cells

FGF-4 Protein, Human, Recombinant

TMPY-05004

Species: Human

Expression System: E. coli

IL-3R alpha/CD123 Protein, Human, Recombinant (His)

TMPY-01410

Species: Human

Expression System: HEK293

FLT3 Ligand Protein, Mouse, Recombinant (hFc)

TMPY-03066

Species: Mouse

Expression System: HEK293

G-CSF Protein, Mouse, Recombinant

TMPY-05636

Species: Mouse

Expression System: HEK293

G-CSF Protein, Human, Recombinant

TMPY-04829

Species: Human

Expression System: HEK293

FLT3 Ligand Protein, Human, Recombinant (His)

TMPY-03215

Species: Human

Expression System: Baculovirus-Insect Cells

FLT3 Ligand Protein, Human, Recombinant

TMPY-06873

Species: Human

Expression System: E. coli

CDCP1 Protein, Rhesus, Recombinant (His)

TMPY-03835

Species: Rhesus

Expression System: HEK293

BMP-4 Protein, Human, Recombinant (E399D)

TMPY-06842

Species: Human

Expression System: E. coli

CDCP1 Protein, Human, Recombinant (His)

TMPY-04298

Species: Human

Expression System: HEK293

CD48 Protein, Human, Recombinant (hFc)

TMPY-03947

Species: Human

Expression System: HEK293

VISTA Protein, Mouse, Recombinant (hFc)

TMPY-00130

Species: Mouse

Expression System: HEK293

CD93/C1qR1 Protein, Human, Recombinant (His)

TMPY-02268

Species: Human

Expression System: HEK293

CD93/C1qR1 Protein, Mouse, Recombinant (hFc)

TMPY-06844

Species: Mouse

Expression System: HEK293

CD93/C1qR1 Protein, Mouse, Recombinant (His)

TMPY-06027

Species: Mouse

Expression System: HEK293

VISTA Protein, Human, Recombinant (His)

TMPY-03219

Species: Human

Expression System: HEK293

LIF Protein, Human, Recombinant (His)

TMPY-03532

Species: Human

Expression System: HEK293

LIF Protein, Human, Recombinant

TMPY-04104

Species: Human

Expression System: HEK293

LIF Protein, Mouse, Recombinant

TMPY-04278

Species: Mouse

Expression System: HEK293

Endoglin/CD105 Protein, Human, Recombinant (His)

TMPY-01384

Species: Human

Expression System: HEK293

IL-3 Protein, Mouse, Recombinant (His)

TMPJ-00051

Species: Mouse

Expression System: Human Cells

TREM-2 Protein, Human, Recombinant (His)

TMPY-01148

Species: Human

Expression System: HEK293

TREM-2 Protein, Mouse, Recombinant (hFc)

TMPY-00432

Species: Mouse

Expression System: HEK293

TREM-2 Protein, Mouse, Recombinant (His)

TMPY-01703

Species: Mouse

Expression System: HEK293

CD166/ALCAM Protein, Human, Recombinant (His)

TMPY-01578

Species: Human

Expression System: HEK293

CD200 Protein, Human, Recombinant (hFc)

TMPY-05446

Species: Human

Expression System: HEK293

M-CSF/CSF1 Protein, Mouse, Recombinant

TMPY-00464

Species: Mouse

Expression System: HEK293

SCF Protein, Human, Recombinant (aa 1-189, His)

TMPY-02170

Species: Human

Expression System: Baculovirus-Insect Cells

FLT3 Protein, Human, Recombinant (T227M, His)

TMPY-01247

Species: Human

Expression System: HEK293

SCF Protein, Mouse, Recombinant (His)

TMPY-02105

Species: Mouse

Expression System: Baculovirus-Insect Cells

PADI4 Protein, Human, Recombinant (His)

TMPY-00021

Species: Human

Expression System: Baculovirus-Insect Cells

GSK3B Protein, Human, Recombinant (His)

TMPY-04356

Species: Human

Expression System: Baculovirus-Insect Cells

TrkA Protein, Human, Recombinant (His)

TMPY-01084

Species: Human

Expression System: HEK293

IL-3 Protein, Human, Recombinant（E. coli）

TMPK-00590

Species: Human

Expression System: E. coli

IL-3 Protein, Cynomolgus, Recombinant (His)

TMPK-00655

Species: Cynomolgus

Expression System: E. coli

IL-3 Protein, Human, Recombinant (His & Avi)

TMPK-00031

Species: Human

Expression System: E. coli

IL-3 Protein, Human, Recombinant (hFc)

TMPK-00033

Species: Human

Expression System: HEK293

IL-3 Protein, Human, Recombinant (His & Avi), Biotinylated

TMPK-00032

Species: Human

Expression System: E. coli

HOXB4 Protein, Human,Recombinant (L175D, E176K, E178K, His)

TMPJ-00879

Species: Human

Expression System: E. coli

IL-3 Protein, Mouse, Recombinant (hFc)

TMPK-00049

Species: Mouse

Expression System: HEK293

CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (hFc & Avi), Biotinylated

TMPK-01002

Species: Human

Expression System: HEK293

CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (aa 65-265, hFc)

TMPK-01004

Species: Human

Expression System: HEK293

CLEC12A/MICL/CLL-1 Protein, Cynomolgus, Recombinant (His)

TMPK-00548

Species: Cynomolgus

Expression System: HEK293

CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His, Avi), Biotinylated

TMPK-01003

Species: Human

Expression System: HEK293

CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (aa 65-265, His)

TMPK-01006

Species: Human

Expression System: HEK293

CLEC12A/MICL/CLL-1 Protein, Mouse, Recombinant (aa 65-267, His)

TMPK-00995

Species: Mouse

Expression System: HEK293

CLEC12A/MICL/CLL-1 Protein, Human, Recombinant (His), FITC-Labeled

TMPK-01005

Species: Human

Expression System: HEK293

CHRDL1 Protein, Mouse, Recombinant (His & Myc)

TMPH-02579

Species: Mouse

Expression System: Baculovirus

YJEFN3 Protein, Human, Recombinant

TMPH-02316

Species: Human

Expression System: E. coli

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カタログ番号	製品名
L8000	Stem Cell Differentiation Compound Library	1213 compounds
	A unique collection of 1213 stem cell differentiation signaling targeted compounds for high throughput and high content screening;
L8110	Reprogramming Compound Library	1840 compounds
	A unique collection of 1840 reprogramming signaling pathway-related bioactive small molecule compounds for high-throughput, high-content screening.
L4000	Bioactive Compound Library	14590 compounds
	A collection of 14590 small molecule compounds with validated activity for high throughput screening (HTS), high content screening (HCS), cell induction, and target identification;
L4010	Bioactive Compounds Library Max	22706 compounds
	A collection of 22706 bioactive compounds for high-throughput screening, high-content screening, cell induction and target identification.
L2600	Neuronal Signaling Compound Library	2540 compounds
	A unique collection of 2540 compounds targeting CNS signaling for high throughput screening (HTS) and high content screening (HCS) for new drugs;
L9840	Anti-Alzheimer's Disease Compound Library	1040 compounds
	A unique collection of 1040 compounds with anti-AD activities or acting on main drug targets of AD can be used for HTS and HCS.